Small business that run their business at home have two major drawbacks. 
A. unprofessional image; for example, a customer, when calling the business owner of a home-based catering service, hears a baby crying in the background and thinks the boundary between business and the owner's personal life is unpleasantly ambiguous. 
B. negative impact on the neighbourhood. For example, workers go to the catering service to help out, park their cars in the neighbourhood, and make other neighbours unable to park their cars.